منابع مشابه
Elastic lever-arm model for myosin V.
We present a mechanochemical model for myosin V, a two-headed processive motor protein. We derive the properties of a dimer from those of an individual head, which we model both with a four-state cycle (detached; attached with ADP.Pi; attached with ADP; and attached without nucleotide) and alternatively with a five-state cycle (where the powerstroke is not tightly coupled to the phosphate relea...
متن کاملMyosin V walks by lever action and Brownian motion.
Myosin V is a molecular motor that moves cargo along actin filaments. Its two heads, each attached to a long and relatively stiff neck, move alternately forward in a "hand-over-hand" fashion. To observe under a microscope how the necks move, we attached a micrometer-sized rod to one of the necks. The leading neck swings unidirectionally forward, whereas the trailing neck, once lifted, undergoes...
متن کاملThe Decision to Lever
We provide an exact performance attribution for levered strategies. The attribution includes some familiar elements: return magnification due to leverage, borrowing costs, trading costs, and the variance drag; while familiar, these elements are sometimes downplayed in backtests of levered strategies. In addition, we find empirically that the covariance between return of the source portfolio and...
متن کاملGranulome facial de Lever
Le granulome facial de Lever se produit le plus souvent chez l'homme de race blanche. Cliniquement, les lésions apparaissent comme des papules érythémateuses, des nodules ou plaques. Le granulome facial est d'étiologie inconnue, mais des facteurs prédisposant sont possibles incluant l'exposition actinique et les traumatismes. La confirmation du diagnostic est faite par une évaluation histologiq...
متن کاملNeurons that swell
ells that passively swell and contract with changes in osmolarity are the key to detecting those changes, say Most cells have at least two mechanisms for maintaining homeostasis in response to changes in salt concentrations. Without these mechanisms, osmotic forces take over: more water and thus less salt outside cells leads water to flood into a cell. But this swelling doesn't occur in most ce...
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ژورنال
عنوان ژورنال: The Musical Times
سال: 1916
ISSN: 0027-4666
DOI: 10.2307/908458